Hello good people. First time contributor. I'm 63 and a moderate/severe persistant member of the asthma club, of which I wish I would'nt qualify. I take Advair/500, Spiriva, Singular and occasional Albuteral and Prednisone, so I'm well stocked. My pulm. put me on Xolair 8 months ago and I can't really say I feel improvement. Could it take even longer to kick in? I've read that it can take months, but how many? I'm so multi-triggered that it's very hard to tell what is effective. A couple caveats – I live in Colorado at 7,600 feet which no one would suggest. Also, I've had open heart surgery last Aug. for a valve. My recovery appears to be excellent. But could my asthma still be compromised by surgery? Please don't ask me to ask my pulm. I respect him but his opinions/guesswork is no more valid then what you veterans can give me. Help. Thank you.