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Breastfed vs Formula and Vaginal vs C-Section delivery

I'm a Registered Respiratory Therapist researching Asthma and Allergies and was wondering if those with asthma or allergies could tell me if they were breastfed or not and if they were delivered via C-section or not?  Thanks for your help.  I will discuss once I get replies,

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  • Excel Well

    Below is the link to the Google Forms Survey to respond to the above questions.  Thanks very much for participating in my survey!

    This research project is posted with permission from The Asthma and Allergy Foundation of America (AAFA). This study is being done by a medical professional and is not affiliated with or endorsed by AAFA in any way. The benefits to you for participating are limited to results given by the researcher. There is a possibility that your participation in this project may contribute to finding out what causes some to have asthma, but the overall impact may be low.
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    Associations between lung and gut microbiome and the risk of developing respiratory allergic disease have been found, indicating that both gut and lung mucosa may function as a single organ, sharing immunological functions and microorganisms.  studied a cohort of infants with cystic fibrosis and discovered a pattern of clusters of bacteria, including potential pathogens such as Enterococcus, which were present in early life in the gut and later in young life in the respiratory tract. In the same study, they showed that changes in diet affected patients’ respiratory microbiome, suggesting a link between nutrition and the development of microbial communities in the respiratory tract.

     
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    Tight Junctions, Leaky Intestines, and Pediatric Diseases

     
    • PMID: 16092447

    Abstract

    Background: Tight junctions (TJs) represent the major barrier within the paracellular pathway between intestinal epithelial cells. Disruption of TJs leads to intestinal hyperpermeability (the so-called "leaky gut") and is implicated in the pathogenesis of several acute and chronic pediatric disease entities that are likely to have their origin during infancy.

    Aim: This review provides an overview of evidence for the role of TJ breakdown in diseases such as systemic inflammatory response syndrome (SIRS), inflammatory bowel disease, type 1 diabetes, allergies, asthma, and autism.

    Conclusion: A better basic understanding of this structure might lead to prevention or treatment of these diseases using nutritional or other means.

    Similar articles

    Image of the epithelial tight junctions:

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    Volume 70, pp 631–659

    Regulation of intestinal epithelial permeability by tight junctions

      • Takuya Suzuki
      1. 1.
      Review

       

      Abstract

      The gastrointestinal epithelium forms the boundary between the body and external environment. It effectively provides a selective permeable barrier that limits the permeation of luminal noxious molecules, such as pathogens, toxins, and antigens, while allowing the appropriate absorption of nutrients and water. This selective permeable barrier is achieved by intercellular tight junction (TJ) structures, which regulate paracellular permeability. Disruption of the intestinal TJ barrier, followed by permeation of luminal noxious molecules, induces a perturbation of the mucosal immune system and inflammation, and can act as a trigger for the development of intestinal and systemic diseases. In this context, much effort has been taken to understand the roles of extracellular factors, including cytokines, pathogens, and food factors, for the regulation of the intestinal TJ barrier. Here, I discuss the regulation of the intestinal TJ barrier together with its implications for the pathogenesis of diseases.

       

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      Intestinal permeability is increased in bronchial asthma

      Abstract

      Background: Increased intestinal permeability has been reported in one study of adult asthmatics.

      Aim: To determine whether children with asthma have altered intestinal permeability.

      Methods: Thirty two asthmatic children, and 32 sex and age matched controls were recruited. The dual sugar (lactulose and mannitol) test was used to evaluate intestinal permeability, and the percentage of ingested lactulose (L) and mannitol (M) in the urine, and the L:M ratio were determined. All patients were skin prick tested for common aeroallergens, and specific IgE to some food items was determined.

      Results: The median value of L in asthmatic children (2.29, IQR 0.91–4.07) was significantly higher than that in controls (0.69, IQR 0.45–1.08), and that of M was almost similar. The ratio L:M was significantly higher in asthmatic children (0.20, IQR 0.11–0.40) than in controls (0.06, IQR 0.04–0.09). Intestinal permeability did not correlate with eczema, inhaled steroids, positive skin prick test to aeroallergens, or severity of asthma.

      Conclusions: Intestinal permeability is increased in children with asthma, suggesting that the whole mucosal system may be affected.

       

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      The best advice I can give anyone with allergies or asthma is to find a Functional Medicine Doctor near you and get to him or her ASAP.  They treat the cause of diseases and not just the symptoms.  The world renowned Cleveland Clinic opened a Functional Medicine Clinic several years ago and they have a waiting listing to get in.

      Curran says that by and large, insurers have been friendly toward CFM. “We have been able to get 95% of the physician office visits covered, and 50% of the nutrition visits covered by insurance. People have this myth that insurance plans won’t pay for these things. But they will.”

      CFM bills the office visits as Level 4 or 5 internal medicine visits.

      “Functional medicine is not considered a specialty. It would be a huge change if it became a specialty and we could bill at specialty rates,” she said. For the foreseeable future, functional medicine will remain part of primary care.

       

      What is Functional Medicine:

      Find a Functional Medicine Practitioner near you:

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      Babies born by cesarean section have greater likelihoods of autoimmune diseases during childhood and later in life.  They also have a gut microbiome that resembles their mother’s skin right after birth. On the other hand, babies that are born vaginally have a gut microbiome that resembles their mothers’ vaginas, and are at lower risk for asthma and allergies.  Given the importance of the microbiome on immune development, many scientists believe that there may be a link between mode of delivery, the initial infant gut microbiome, and normal immune development.