So we had our first couple of freezing nights down here in the Deep South … although some of you have already had way colder weather. I was glad that we have a good habit instilled in DD to never leave her epinephrine auto-injectors in the car or in a book bag that stays in the car …
But I was ALSO very reassured by a recent study that I read about the effects on . According to the press release about the study, the auto-injector still fired.
[The research indicated] freezing did not affect how the EAIs functioned once they were thawed.
The research only applies to the brand EpiPen, so more research would need to be done before the findings could apply to other brand names.
Heat, on the other hand, was not so kind. A study on the reported on the American Academy of Allergy, Asthma & Immunology website said this:
The study found even a single, short-time exposure to heat in a car during a sunny day can decrease epinephrine concentration in autoinjectors. If such degradation turns out to be progressive or cumulative, it could result in significant underdosage of epinephrine during anaphylaxis.
Kids With Food Allergies (part of AAFA) has been following this a long time. They had an older blog post covering as well.
The press release about cold and freezing said this:
If you have an EAI that was unintentionally frozen, and you experience an anaphylactic reaction, it’s better to use a ‘thawed’ device than nothing at all. However, you should talk with your allergist about a prescription for a new device.
Have you ever accidentally left an epinephrine auto-injector in your car? What did your allergist suggest? What are some ways that you protect your auto-injectors from extreme temps?