I have been on several antihistamines over the years and they eventually lose effectiveness. All of these medications were prescribed by my allergist. Over the years I have taken Claritin, Allegra, Zyrtec, Xyzal, a combination of Claritin and Allegra, a combination of Zyrtec and Xyzal, a combination of Xyzal and Allegra, and etc. None of them prevent allergy symptoms anymore. Benadryl has also lost effectiveness and now only 75mg of Benadryl helps my allergy symptoms. I can only take this dose at bedtime. I also use Patanase and Nasonex on a daily basis.
What antihistamine(s) have you found helpful?
Have you discontinued using an antihistamine because it has become ineffective?